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TP1863L |
Glucagon (19-29), human acetate
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Glucagon Receptor
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Glucagon (19-29), human acetate a COOH-terminal fragment processed from glucagon, is a potent and efficient inhibitor of insulin secretion. |
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T15389L |
Glucagon (1-29), bovine, human, porcine hydrochloride
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Porcine glucagon hydrochloride,Glucagon hydrochloride |
Glucocorticoid Receptor
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Glucagon Receptor
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Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. It activates HNF4α and increases HNF4α phosphorylation. Glucagon (1-29), bovine, human, porcine hydrochloride(Po... |
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TP1863 |
Glucagon (19-29), human
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Glucagon is a 29-amino-acid peptide hormone liberated in the alpha cells of the islets of Langerhans. Glucagon-producing alpha cells represent one of the earliest populations of detectable islet cells in the developing e... |
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T78059 |
Glucagon (Human)
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Hyperglycemic-glycogenolytic factor,Glukagon |
Others
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Glucagon significantly impacts protein and amino acid metabolism. It hinders the integration of amino acids into the proteins of the liver, muscle, and pancreas, augmenting nitrogen excretion and stimulating hepatic urea... |
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T15389 |
Glucagon (1-29), bovine, human, porcine
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Porcine glucagon,Glucagon |
Others
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Glucagon is a peptide hormone, produced by pancreatic α-cells. Glucagon reduces the activity of HNF-4. Glucagon stimulates gluconeogenesis. Glucagon enhances HNF4α phosphorylation. |
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TP1148L |
Glucagon-like peptide 1 (1-37), human acetate
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Glucagon Receptor
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Glucagon-like peptide 1 (1-37), human acetate is a highly potent the GLP-1 receptor agonist. |
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TP1487 |
Glucagon-Like Peptide (GLP) II, human
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Glucagon-like peptide 2 (GLP-2) is a recently identified intestinal epithelium-specific growth factor that has been shown to reduce the severity of inflammatory disorders of the intestine in rodent models. Currently Gluc... |
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T3984 |
GLP-1(7-36), amide
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MKC 253,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide |
Glucagon Receptor
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GLP-1(7-36), amide (MKC 253) is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays various antidiabetic effects by potentiating glucose-... |
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TP1148 |
Glucagon-like peptide 1 (1-37), human
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HuGLP-1 |
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Glucagon-like peptide 1 (1-37), human is a highly potent agonist of the GLP-1 receptor.Pancreatic hormone synthesized by post-translational processing of proglucagon. Unlike truncated forms of GLP-1, it has no effect on ... |
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TP1147 |
Glucagon-like peptide 1 (1-37), human TFA
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HuGLP-1 TFA |
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Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor, it is a kind of pancreatic hormone synthesized by post-translational processing of proglucagon. |
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TP1157 |
GLP-2(1-33)(human)
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GLP-2 (human),Glucagon-like peptide 2 (human) |
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GLP-2(1-33) (human) is an enteroendocrine hormone which stimulates the growth of the intestinal epithelium. |
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T80453 |
GLP-1 (1-36) amide (human, rat)
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Glucagon-like Peptide 1 (1-36) amide (human, rat) |
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GLP-1 (1-36) amide (human, rat) is a molecular variant of the GLP-1 (7-36) amide and has the capacity to stimulate [14C]aminopyrine accumulation in enzymatically dispersed, enriched rat parietal cells [1]. |
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T82309 |
GLP-1 (1-36) amide (human, rat) (TFA)
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Glucagon-like Peptide 1 (1-36) amide (human, rat) (TFA) |
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GLP-1 (1-36) amide (human, rat) TFA, a molecular variant of GLP-1 (7-36) amide, can induce [14C]aminopyrine accumulation in enzymatically dispersed enriched rat parietal cells [1]. |
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T76332 |
Biotinyl-Glucagon (1-29), human, bovine, porcine
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Biotinyl-Glucagon (1-29), encompassing human, bovine, and porcine versions, is a biotinylated form of glucagon. This peptide hormone, synthesized by the pancreas's α-cells, elevates glucose and fatty acid levels in the b... |
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T83550 |
(Asp28)-Glucagon (1-29) (human, rat, porcine)
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"(Asp28)-Glucagon (1-29) (human, rat, porcine)" is an analog of glucagon with an aspartic acid (Asp) substitution at position 28, notably enhancing its aqueous solubility at physiological pH levels while retaining glucag... |
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T76628 |
(Met(O)27)-Glucagon (1-29) (human, rat, porcine)
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(Met(O)27)-Glucagon (1-29) (human, rat, porcine) is a modified version of glucagon that exhibits the same maximum glucose-synthesizing activity in rat hepatocytes as its native counterpart. However, its reduced potency i... |
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T76330 |
Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide
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Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide, a biotin-labeled variant of glucagon-like peptide-1-(7-36), is a gastrointestinal peptide recognized for its antidiabetogenic properties, including the ability to e... |
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T76085 |
Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human
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Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human, is a human GLP-1 (7-36) amide that has been biotinylated at the C-terminal. |
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T7364 |
NNC-0640
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Glucagon Receptor
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NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM. |
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T22893 |
L-168049
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L-168,049 |
Glucagon Receptor
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L-168049 is a selective and non-competitive antagonist of human glucagon receptor with IC50s of 3.7 nM, 63 nM, and 60 nM for human, murine, and canine, respectively. |
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T36579 |
GLP-1R Agonist DMB
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Glucagon Receptor
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GLP-1R Agonist DMB is an agonist of glucagon-like peptide 1 receptor (GLP-1R; KB = 26.3 nM for the recombinant human receptor). |
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T19850 |
Semaglutide
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Glucagon Receptor
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Semaglutide is a glucagon-like peptide 1 receptor (GLP-1R) agonist(EC50 of 6.2 pM in a reporter assay using BHK cells expressing the human receptor). |
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T3422 |
GRA Ex-25
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GRA-Ex-25 |
Glucagon Receptor
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GRA Ex-25 (GRA-Ex-25) is an inhibitor of glucagon receptor. |
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T37223 |
Glucagon Receptor Antagonist I
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Glucagon receptor antagonist I is a competitive antagonist of the glucagon receptor (GCGR; IC50 = 181 nM). It blocks glucagon-induced glycogenolysis in primary human hepatocytes and isolated liver. Glucagon receptor anta... |
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T36428 |
PACAP-related Peptide (human) (trifluoroacetate salt)
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PACAP
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PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adeny... |
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T81585 |
Oxyntomodulin (human, mouse, rat)
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Proglucagon (33-69) |
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Oxyntomodulin (human, mouse, rat) (Proglucagon [33-69]), a derivative of the glucagon progenitor, encompasses the full sequence of glucagon along with an additional C-terminal octapeptide, culminating in a structure of 3... |
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T80565 |
Gulgafafusp alfa
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Gulgafafusp alfa is a human IgG2κ monoclonal antibody that selectively binds to the glucagon-like peptide 1 receptor (GLP1R) [1]. |
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T36072 |
Skyrin
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Endothianin,Rhodophyscin |
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Skyrin is a fungal metabolite characterized by a bisanthraquinone structure. It interferes with glucagon signaling through adenylate cyclase without binding to the glucagon receptor. At 10 μM, skyrin reduces both glucago... |
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T77791 |
Dasiglucagon
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Dasiglucagon is a stable human glucagon peptide analog that is rapid and effective in the treatment of severe hypoglycemia. |
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T72621 |
GCGR antagonist 2
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GCGR Antagonist 2, a Furan-2-carbohydrazide, serves as an orally active antagonist of the glucagon receptor. It exhibits affinity for the human glucagon receptor (hGluR) with a dissociation constant (Kd) of 2.3 nM and de... |
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T37577 |
Glycogen Phosphorylase Inhibitor
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Glycogen phosphorylase in the liver, muscle, and brain initiate glycogenolysis by releasing glucose-1-phosphate from glycogen. Glycogen phosphorylase inhibitor is a cell-permeable acyl urea first identified as an inhibit... |
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T80149 |
GRPP (human)
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GRPP (human), a 30-amino-acid peptide derived from Gcg, modestly elevates plasma insulin levels while reducing plasma glucagon concentrations. However, GRPP (human) has no impact on insulin secretion within rat islets [1... |
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T75822 |
GLP-1(9-36)amide TFA
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GLP-1(9-36)amide TFA, a predominant metabolite of glucagon-like peptide-1-(7-36)amide synthesized through dipeptidyl peptidase-4 (DPP-4) activity, functions as an antagonist to the human pancreatic GLP-1 receptor [1] [2]... |
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T80084 |
Retatrutide acetate
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LY3437943 acetate |
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Retatrutide acetate (LY3437943) is a peptide that serves as a triple agonist for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). ... |
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T76862 |
Crotedumab
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Crotedumab (REGN1193), a fully human IgG4 monoclonal antibody, selectively binds to and inhibits the glucagon receptor (GCGR) with a dissociation constant (K D) of 0.1 nM, making it a potent candidate for diabetes resear... |
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T36380 |
GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)
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GLP-1 amide is a peptide hormone cleaved from proglucagon in the pancreas.1,2 Mice lacking the glucagon receptor (Gcgr-/-) have approximately nine-fold higher levels of total GLP-1 amide, including GLP-1 (1-36) amide and... |
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T75787 |
Amylin, amide, human TFA
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Amylin, amide, human TFA, a 37-amino acid polypeptide, functions as a pancreatic hormone that is cosecreted with insulin, playing distinct roles in metabolism and glucose homeostasis. It regulates blood sugar by inhibiti... |
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T76333 |
(Ser8)-GLP-1 (7-36) amide, human
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(Ser8)-GLP-1 (7-36) amide, human is a glucagon-like peptide-1 amide originating from glucagonogen, itself a cleavage product of the GLP-1 (1-36) amide peptide. This entero-insulinotropic hormone facilitates glucose-depen... |
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T21691 |
NVP DPP 728 dihydrochloride
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NVP-DPP728 is a potent, reversible, nitrile-dependent inhibitor of dipeptidyl peptidase IV (DPP-IV), demonstrating an inhibition constant (K i) of 11 nM for human DPP-IV amidolytic activity. By inhibiting the degradation... |
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T73694 |
Albiglutide TFA
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Albiglutide TFA, a glucagon-like peptide (GLP)-1 mimetic, is a long acting GLP-1 receptor agonist. Albiglutide TFA significantly reduces glycosylated hemoglobin (A1C). Albiglutide TFA can be used for type 2 diabetes (T2D... |
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TP1302 |
Somatostatin
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Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues that regulates the endocrine system. It is secreted by the D cells of the islets to ... |
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T36427 |
PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)
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PACAP
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Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expres... |
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T83906 |
Tirzepatide sodium
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LY3298176 |
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Tirzepatide acts as an agonist for both the glucagon-like peptide 1 receptor (GLP-1R) and G protein-coupled receptor 119 (GPR119), effectively inducing cAMP production in HEK293 cells that express either human GLP-1R or ... |
